What is the best synonym for 'vindicate'?

The term 'vindicate' means to clear someone of blame or suspicion, or to justify or prove something to be right or reasonable. In this context, 'exonerate' is the best synonym as it specifically refers to the act of freeing someone from blame or a charge of wrongdoing. When one is exonerated, they are often proven innocent of allegations that have been made against them, which aligns closely with the meaning of 'vindicate.'

Other choices do not share this meaning. For example, 'accuse' involves charging someone with a wrongdoing, and 'prosecute' implies taking legal action against someone—both opposing the idea of vindication. Likewise, 'condemn' means to express strong disapproval or to denounce someone, which is contrary to the notion of clearing someone’s name or providing justification. Therefore, 'exonerate' effectively captures the essence of 'vindicate.'